Five years ago, fundamental changes began in Russian healthcare, one of which was the creation of large national medical research centers. At the suggestion of Minister Veronika Skvortsova three well-known and respected institutions united. In 2014 P. Hertsen Moscow Oncology Research Institute, N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology, A. Tsyb Medical Radiological Research Centre merged into National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (NMRRC). Of course, at the beginning of the journey there was a lot of reflection on how to preserve the best in this new configuration and not to lose tradition. Today, when the problem of the fight against cancer around the world has come to the fore, and has become a national priority in our country, we understand how timely the decision to create the first such oncology cluster in Russia was. Today, our joint center employs more than three thousand people, we perform more than 16,000 operations per year, more than 3,000,000 studies, and we test a large number of new medicines and modern techniques. Our specialists perform unique operations: completely restore speech and normal functions of the tongue, pharynx, larynx from the biomaterial of the patient himself; we carry out radioembolization with the help of domestic microspheres developed by our centre, we do brachytherapy on the liver and pancreas using the domestic radioisotope iodine 125.Show
Proper routing between the branches of the Center allows a patient who comes to us to receive a full range of combined and complex diagnostic and treatment procedures, including surgery, various options for chemotherapy and radiation therapy. There are wide opportunities for international cooperation - we give our expert opinion to colleagues from respected foreign cancer centers, with which we have signed several agreements on real collaborative projects over the past two years. A common telemedicine platform for exchanging morphological and clinical data is being created; we are planning to open the second proton therapy centre and the first heavy ion therapy center (in the post-Soviet states) in collaboration with Japanese colleagues. People come to us for experience and they are amazed to see the significant results we have been able to achieve in just five years. This has become possible thanks to the synergy of our merger and state support of oncology. Efficiency and targeting, proclaimed in the new national cancer control program, and multidisciplinarity in solving tasks have become a reliable basis for the implementation of the program.
I am sure we can do a lot together!
In 2019, N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation celebrated its fortieth anniversary. Since the beginning, our institute has been a leading institution in the field of urology, it has trained several generations of first-class specialists not only for Russia, but also for the countries of the Commonwealth of Independent States (CIS). It was in our Institute where a unique school of Russian urology was founded. For the anniversary, the reconstruction was completed on the basis of the Federal targeted investment program for the construction and reconstruction of buildings and structures of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology, new unique scientific and clinical laboratories were opened and renovated. On February 18, 2019, the inauguration of the memorial plaque in memory of Academician Nikolai Alekseevich Lopatkin took place at N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology. The famous urologist, founder of the Research Institute of Urology, would have turned 95 years old. Minister of Health of the Russian Federation (from 2012 to 2020) Veronika Skvortsova took part in the ceremony.Show
Now our Institute is still the leading federal research institution for urology and andrology in the Russian Federation, supervising scientific research and specialized medical care in this area of health care. Doctors perform a wide range of urological, oncourological, endourological and neuro-urological interventions and provide medical assistance in the field of pediatric urology and kidney transplantation. The Institute conducts research in key areas of urology: urolithiasis, urinary disorders of various nature, urologic cancers, infectious and inflammatory diseases, renal failure, male infertility, androgen deficiency, etc. The basis for scientific work is a modern research complex with laboratories of pathomorphology, molecular genetics, general clinical research, microbiology, liquid chromatography, cell technologies, experimental modeling of urological diseases. The Research Institute of Urology has a high scientific and clinical potential. The founder of the institute, academician N.A. Lopatkin established Russian urological service, where the Research Institute of Urology played the role of a scientific coordination center.
Today, 18 Doctors of Medical Sciences, 44 PhDs and medical doctors of the highest qualification grade work here. Every year the institute performs 4,000 surgical operations 23,000 diagnostic tests 319,000 laboratory tests 87,000 anatomical pathological examinations. More than 70% of operations are performed using minimally invasive endo- and laparoscopic technologies. More than 14,000 patients receive outpatient care. The doctors and medical staff of our Institute understands that the greatest success of our work is the recovery of our patients. Doctors and nurses' love for work, responsibility and loyalty to traditions have ensured the leadership of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology in the field of urology for more than 40 years. Stay healthy!
Director of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology - branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation Corresponding member of RAS Oleg Apolikhin
N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology provides treatment of complex cases of urolithiasis in adults and children, using all types of surgical operations, including open, percutaneous, retrograde intrarenal interventions and external lithotripsy. Annually, 1,200 patients with urolithiasis undergo surgery, including 600 percutaneous operations for large and coral kidney stones. Methods for the diagnosis and correction of metabolic disorders have been developed to prevent recurrence of urolithiasis taking into account genetic, nutritional and metabolic risk factors.
Advanced studies of the peculiarities of metabolic disorders in the pathogenesis of urolithiasis and the role of intestinal microbiota in kidney stone formation are carried out. Specialists have developed high-precision models for predicting the chemical composition of kidney stones in vivo by metabolic indicators and original methods for assessing nutritional factors and remote monitoring of the treatment of urolithiasis. The role of genetic risk factors and comorbidity in kidney stone formation is also being studied.
N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology performs a wide range of reconstructive plastic interventions on the urinary tract of adults and children: all types of urinary diversion, operations for urinary incontinence, urinary fistulas, strictures of the ureters and urethra, including the use of vascularized flaps, buccal mucosa, and microsurgical techniques. An integrated approach has been developed for preoperative examination and the implementation of various methods of reconstructive plastic surgery when urologists work in collaboration with traumatologists for significant pelvic injuries in men, women and children.
Areas of work:
• Diagnostics, conservative and surgical treatment of diseases of the prostate and scrotum organs, erectile dysfunction, male infertility, correction of metabolic syndrome and androgen deficiency
• Genetic diagnosis of hereditary syndromes in male infertility.
• Sperm collection for assisted reproductive technologies using microsurgical techniques.
Annually, more than 1,200 oncourological patients are treated at the Center, 1,140 operations are performed, including over 220 for kidney cancer, 140 kidney resections, about 300 radical prostatectomies and up to 40 cystectomies. Most operations are performed using laparoscopic and minimally invasive technologies. Modern molecular genetic markers, imaging tools and fusion biopsy are used to diagnose oncological diseases.
Endourology and minimally invasive surgery
A wide range of high-tech endo- and laparoscopic interventions for urolithiasis, urological cancers, benign hyperplasia and prostate cancer are performed. 70% of all inpatient operations are carried out using endoscopic and minimally invasive technologies. Retrograde intrarenal surgery for malignant neoplasms of the urinary tract is a new promising method. The doctors at the Institute perform permanent 125I brachytherapy for prostate cancer, radiofrequency ablation of kidney tumors, photodynamic therapy for kidney and bladder cancer.
N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology has one of the most advanced scientific and practical laboratories in the field of urodynamics and neurourology in Eastern Europe and the CIS countries. A comprehensive and differential research into the causes of impaired urination is carried out using combined urodynamic, video urodynamic and neurophysiological studies.
The doctors here administer conservative, minimally invasive and surgical treatment of urination disorders in adults and children using behavioral therapy, various training methods, biological feedback, magnetic therapy, neuromodulation. The latest techniques in the treatment of urination disorders can help to restore lost urination, get rid of suprapubic urinary catheters, eliminate pelvic pain, and cope with long-term symptoms of cystitis and prostatitis. N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology is one of the world leaders in the use of botulinum toxin type A in urology (more than 2000 observations).
Pediatric Uroandrology Department of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology applies an individual approach to the treatment of each little patient, since many surgical interventions for the correction of congenital defects and anomalies of the genitourinary system in children are carried out taking into account their age characteristics. More than 600 surgical interventions are performed annually in children with various urological diseases, of which more than 200 are minimally invasive. The main area of work is anomalies in the development of the genitourinary organs, including impaired penile formation and bladder exstrophy: 180 and 25 operations per year, respectively. The Institute is a leader in the treatment of urolithiasis in children, including extracorporeal lithotripsy and percutaneous surgery. Coral-shaped stones are removed through a separate puncture, without open interventions with the most minimally invasive methods, with good long-term results (nephrolitholapaxia, contact ureterolithotripsy, etc.). Extracorporeal shock wave lithotripsy - crushing stones with directed ultrasound impulses - is successfully used.
The first kidney transplant at N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology was performed in 1966. For the contribution made to the development of clinical transplantology, the team led by the academician N.A. Lopatkin was awarded the USSR State Prize. Since that time, transplantation has established itself as a highly effective method of replacing lost kidney function. Coordinated work of surgeons with great experience in treating patients with diseases of the urinary system and chronic renal failure lets them perform complex allotransplantation (transplantation of a related kidney from a living donor, transplantation of a cadaveric kidney). About 60 kidney transplants are performed annually, including with AB0 incompatibility. More than 8,000 hemodialysis sessions are conducted in patients with chronic renal failure (CRF). The Institute staff has experience in kidney transplantation in children. The doctors do research into the diagnosis and treatment of rejection reactions during kidney transplantation, as well as the study of the effect of various uremic toxins on the patient’s body with the development of chronic renal failure and detoxification methods.
N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology has created a unique scientific-experimental and clinical complex with laboratories of pathomorphology, molecular genetics, general clinical research, microbiology, liquid chromatography, cell technology and experimental modeling of urological diseases. It is possible to assess the pathological process: genome, proteome, metabolol, microbiome, nutria, which is necessary for identifying and correcting existing changes in a wide range of urological diseases in adults and children.
Close interaction between the clinic and the laboratories of the complex directs the vector of scientific research to practice and shortens the path from development to clinical application. This makes it possible to quickly test and implement advanced biomedical technologies, allowing clinicians to test hypotheses in various model systems and quickly reveal the results obtained in the interests of healthcare.
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